Urinary symptoms decrease quality of life in patients with Parkinson’s disease




Esmeralda Gracián-Castro, Facultad de Medicina, Universidad Popular Autónoma del Estado de Puebla, Puebla, México
Nancy R. Bertado-Ramírez, Dirección de Educación e Investigación en Salud, Hospital de Especialidades Gral. de Div. Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, México
Arturo García-Galicia, Dirección de Educación e Investigación en Salud, Unidad Médica de Alta Especialidad, Hospital de Especialidades de Puebla, Centro Médico Nacional Gral. de Div. Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, México
Daniel Núñez-Corona, Departamento Clínico de Urología, Centro Médico Nacional, Hospital de Especialidades Gral. de Div. Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, México
Gisela Alonso-Torres, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, México
Álvaro J. Montiel-Jarquín, Dirección de Educación e Investigación en Salud, Unidad Médica de Alta Especialidad, Hospital de Especialidades de Puebla, Centro Médico Nacional Gral. de Div. Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, México
Jorge Loría-Castellanos, Coordinación de Proyectos Especiales en Salud, Instituto Mexicano del Seguro Social. Ciudad de México, México


Introduction: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects multiple systems manifesting with motor and non-motor symptoms. Urinary symptoms are the most prevalent non-motor manifestations. Objective: To compare the quality of life (QoL) in patients with PD according to their urinary symptomatology in a tertiary care hospital. Methods: Comparative, cross-sectional, prospective study in a third level hospital in Puebla, Mexico. Patients with a diagnosis of PD, older than 30 years, both sexes, were included. The IPSS and SF-36 scales were applied. Descriptive statistics, Kruskal-Wallis and Spearman’s rho were used. Results: Thirty-seven patients were evaluated, 59.5% male, mean age 62.3 years (range: 43-84; SD: 10.79). Differences in SF-36 and IPSS were significant in the pain and social function domains (p < 0.05). The correlation between the domain’s physical role, pain, social function, and vitality from IPSS was significant with rho scores from 0.28 to 0.4. The correlation between the impact on QoL by SF-36 and IPSS was not significant (p > 0.05) except in the emotional role domain. Conclusions: Urinary symptoms affect QoL in the domains pain, social function, physical role, and vitality.



Keywords: Quality of life. Parkinson disease. Lower urinary tract symptoms.