Evaluation of physiological metabolic changes in dogs 60 days of age exposed to direct oxygen tracheostomy




Rosa E. Soriano-Rosales, Centro de Investigación Traslacional, Instituto Nacional de Pediatría, Ciudad de México, México
Beatriz E. Pérez-Guillé, Centro de Investigación Traslacional, Instituto Nacional de Pediatría, Ciudad de México, México
Emilio Arch-Tirado, Centro Neurológico, Centro Médico ABC, Santa Fe, Ciudad de México. México
Antonio Verduzco-Mendoza, División de Biotecnología-Bioterio y Cirugía Experimental, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra. Ciudad de México, México
Pamela Sánchez-Pérez, Centro de Investigación Traslacional, Instituto Nacional de Pediatría, Ciudad de México, México


Background: Blood gas analysis is used to monitor gas exchange and homeostasis in acid-base balance. Objective: To evaluate changes in blood gases with tracheostomy puppies directly exposed to oxygen. Twelve puppies of 60 days of age were used, where each one received a tracheotomy and 10 cm from it, a tracheal tube with an O2 concentration of 100% at 3 liters was placed; venous samples were taken before anesthesia, with an exposed trachea, closing the tracheostomy and post-anesthesia recovery. Methods: We used a blood gas analyzer. Statistics were done with t Student’s paired, as box and standard error charts were made. The pO2 rises and falls along the four measurements, pCO2 values have a sinusoid tendency. The values of pCO2 and pO2 behave inversely during the first two blood takes; there were variations in the values of pO2 and pCO2, SO2 and TCO2 throughout surgery. Results: Glucose values present a bell-shaped behavior and lactate a U-shaped one. The pH and HCO3 showed no significant differences. There were statistical variations for sodium, potassium, calcium, and hematocrit. Conclusions: The dog is a good animal model for gas exchange in tracheal surgery studies.



Keywords: Blood gases. Trachea. Surgery. Dogs. Oxygen.